73 Results for "

Garcinia cambogia Desr.

" in MedChemExpress (MCE) Product Catalog:
Products (73)

73 Results for "Garcinia cambogia Desr." in MCE Product Catalog:

6
Gambogic Acid
Gambogic Acid
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6 Publications Verification
Cat. No.: HY-N0087
CAS No.: 2752-65-0
Synonyms: Beta-Guttiferrin
Category:  

Natural Products Guttiferae Plants Garcinia hanburyi Hook. f. Disease Research Fields Cancer

Target:  

Bcl-2 Family Autophagy

Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM.
5
Garcinol
Garcinol
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5 Cited Publications
Cat. No.: HY-107569
CAS No.: 78824-30-3
Purity:  ≥99.0%
Category:  

Guttiferae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Garcinia indica

Target:  

Cholinesterase (ChE) Histone Acetyltransferase Apoptosis Endogenous Metabolite

Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .
2
Garcinone C
Garcinone C
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2 Cited Publications
Cat. No.: HY-N6954
CAS No.: 76996-27-5
Category:  

other families Xanthones Garcinia oblongifolia Champ. ex Benth. Guttiferae Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

ATM/ATR STAT CDK Hedgehog

Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
1
Hydroxycitric acid tripotassium
Hydroxycitric acid tripotassium
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1 Cited Publications
Cat. No.: HY-W338584
CAS No.: 232281-44-6
Tripotassium hydroxycitrate is an orally active, multi-target, multi-bioactive organic acid. Tripotassium hydroxycitrate activates Nrf2 and its downstream molecule GPX4, increases glutathione levels, and thereby inhibits ferroptosis. Tripotassium hydroxycitrate activates the Nrf2/Keap1 and ACLY/NF-κB signaling pathways, upregulates the activities of antioxidant enzymes such as superoxide dismutase, reduces MDA content, thereby alleviating oxidative stress and renal tubular epithelial cell apoptosis, and improves pulmonary vascular and right ventricular remodeling. Tripotassium hydroxycitrate activates both the AMPK and mTORC1/S6K pathways, triggers the unfolded protein response, arrests the cancer cell cycle, and induces DNA fragmentation .
1
Morellic acid
Morellic acid
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1 Cited Publications
Cat. No.: HY-N4094
CAS No.: 5304-71-2
Category:  

Natural Products other families Monophenols Phenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity .
Macurin
Macurin
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Cat. No.: HY-N3347
CAS No.: 519-34-6
Synonyms: Maclurin
Category:  

Garcinia lancilimba C. Y. Wu ex Y. H. Li Guttiferae Phenols Polyphenols Plants

Target:  

Others

Macurin is a xanthone that can be isolated from Garcinia lancilimba .
Garcinia cambogia extract
Garcinia cambogia extract
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Cat. No.: HY-N14035
CAS No.: 90045-23-1
Category:  

Natural Products Guttiferae Garcinia cambogia Desr. Plants

Target:  

FABP PPAR

Garcinia cambogia extract is an orally active anti-obesity agent . Garcinia cambogia extract upregulates the gene expression of aP2, SREBP1c, PPARγ2 and C/EBPα. Garcinia cambogia extract reduces the rate of body weight gain, visceral fat accumulation, lipid levels in blood and liver, as well as plasma insulin and leptin levels . Garcinia cambogia extract ameliorates high-fat diet-induced obesity .
(-)-Hydroxycitric acid lactone
(-)-Hydroxycitric acid lactone
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Cat. No.: HY-N7347
CAS No.: 27750-13-6
Synonyms: Garcinia lactone
Category:  

other families Ketones, Aldehydes, Acids Metabolic Disease Plants Disease Research Fields

Target:  

ATP Citrate Lyase

(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis .
9-Hydroxycalabaxanthone
9-Hydroxycalabaxanthone
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Cat. No.: HY-N2795
CAS No.: 35349-68-9
Synonyms: Xanthone I
Target:  

Parasite Bacterial

연구분야:  

Infection

9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) .
Neosmitilbin
Neosmitilbin
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Cat. No.: HY-N5115
CAS No.: 54081-47-9
Category:  

Flavanonols other families Flavonoids Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Others

Neosmitilbin is isolated from Garcinia mangostana.
Cowaxanthone B
Cowaxanthone B
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Cat. No.: HY-N6248
CAS No.: 212842-64-3
Category:  

Infection other families Xanthones Phenols Polyphenols Plants Disease Research Fields

Target:  

Bacterial

Cowaxanthone B is a xanthone isolated from the fruits of Garcinia cowa. Cowaxanthone B has weak antibacterial activity .
R-30-Hydroxygambogic acid
R-30-Hydroxygambogic acid
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Cat. No.: HY-N10678
CAS No.: 881027-35-6
Category:  

Ketones, Aldehydes, Acids Guttiferae Plants Garcinia hanburyi Hook. f.

Target:  

Others

R-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. R-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC50 values of 2.89 and 1.27 μM for K562/R and K562/S, respectively. R-30-Hydroxygambogic acid can be used for the research of cancer .
1,3,5,6-Tetrahydroxyxanthone
1,3,5,6-Tetrahydroxyxanthone
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Cat. No.: HY-N9113
CAS No.: 5084-31-1
Category:  

Flavonoids Guttiferae Hyperlcurn perforatum L. Plants Other Flavonoids

Target:  

Others

1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats .
4-Methylsyringol
4-Methylsyringol
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Cat. No.: HY-W100715
CAS No.: 6638-05-7
Category:  

Davalliaceae Davallia trichomanoides Blume Plants

Target:  

Others

4-Methylsyringol is a phenolic syringol derivative found in a variety of plants. Phenolic compounds are widely present in food and plants and have high synthetic, medicinal, and industrial value. Polyphenols are compounds with various phenolic functions. Natural polyphenols can regulate the cell cycle, induce apoptosis, inhibit cell adhesion, migration, proliferation, and differentiation, and possess a variety of biological activities such as antioxidation, anti-inflammation, anticancer, and antimutagenic effects .
Macurin (Standard)
Macurin (Standard)
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Cat. No.: HY-N3347R
CAS No.: 519-34-6
Synonyms: Maclurin (Standard)
Category:  

Garcinia lancilimba C. Y. Wu ex Y. H. Li Guttiferae Phenols Polyphenols Plants

Target:  

Reference Standards Others

Macurin is a xanthone that can be isolated from Garcinia lancilimba .
10α-Hydroxyepigambogic acid
10α-Hydroxyepigambogic acid
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Cat. No.: HY-N10673
CAS No.: 1164201-85-7
Category:  

Natural Products Guttiferae Celastraceae Plants Tripterygium wilfordii Hook. f. Garcinia hanburyi Hook. f.

Target:  

Others

10α-Hydroxyepigambogic acid can be extracted from Garcinia hanburyi. 10α-Hydroxyepigambogic acid can be used in the research of tumors .
Garcinol (Standard)
Garcinol (Standard)
0 Images
Cat. No.: HY-107569R
CAS No.: 78824-30-3
Category:  

Guttiferae Phenols Polyphenols Plants Garcinia indica

Target:  

Cholinesterase (ChE) Histone Acetyltransferase Apoptosis Endogenous Metabolite Reference Standards

Garcinol (Standard) is the analytical standard of Garcinol. This product is intended for research and analytical applications. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .
Cotoin
Cotoin
0 Images
Cat. No.: HY-N3637
CAS No.: 479-21-0
Category:  

Natural Products other families Metabolic Disease Phenols Polyphenols Plants Disease Research Fields

Target:  

Others

Cotoin is a natural product isolated from the stem bark of Garcinia virgate .
(+)-Volkensiflavone
(+)-Volkensiflavone
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Cat. No.: HY-124537
CAS No.: 27542-37-6
Category:  

Garcinia livingstonei T.Anderson Flavonoids Guttiferae Plants Biflavones

Target:  

Others

(+)-Volkensiflavone is a biflavonoid, that can be isolated from the fruits of Garcinia livingstonei (Clusiaceae) .
3-Prenyl-2,4,6-trihydroxybenzophenone
3-Prenyl-2,4,6-trihydroxybenzophenone
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Cat. No.: HY-N1868
CAS No.: 93796-20-4
Category:  

Xanthones Guttiferae Phenols Plants Garcinia cowa Roxb.

Target:  

Others

3-Prenyl-2,4,6-trihydroxybenzophenone is a Xanthones product that can be isolated from the herbs of Garcinia cowa .
Assay Types